An Intrathecally Located Broken Catheter Used for an Intrathecal Drug Delivery System

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An Intrathecally Located Broken Catheter Used for an Intrathecal Drug Delivery System

The intrathecal drug delivery system (ITDDS), an effective treatment tool for intractable spasticity and pain, is associated with various complications but breakage of the catheter is rare. We report the case of a 50-yr-old man with ITDDS, in whom an intrathecal catheter was severed, resulting in a 28.6-cm-long intrathecal fragment. The catheter completely retracted into the intrathecal space f...

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Ion-exchange, an Approach to Prepare an Oral Floating Drug Delivery System for Diclofenac

Using ion-exchange resins, a multiple-unit type of oral floating dosage system has been prepared to prolong gastric emptying time of dosage form. The system is composed of beads of drug-resin complex, which are loaded with bicarbonate ions and coated with a hydrophobic polymer. The system is so designed that when the beads reach the stomach, chloride ions are exchanged with bicarbonate and drug...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 2012

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.2012.27.10.1278